Brief summary:  (purpose, learnings and how it supports the ALTERNATIVE)

The objectives of this webinar are to raise awareness about the cardiotoxicity induced by environmental chemicals and to highlight the challenges/knowledge gaps in assessing cardiotoxicity for regulatory purposes. Additionally, the non-animal based methods that are being developed in H2020 European project ALTERNATIVE and their collective regulatory acceptance in light of current difficulties will be presented and discussed. We anticipate audiences from a wide range of areas and inputs received during the discussion session will be used to effectively realize the ultimate goal of the project ALTERNATIVE, which is to develop a novel platform to detect the cardiotoxicity of chemicals in a robust and cost effective manner.

Agenda:

• Epidemiological evidence for cardiotoxicity induced by chemicals (20 min)
• The ALTERNATIVE project and regulatory uptake of ALTERNATIVE platform (30 min)
• Computational tools to assess cardiotoxicity (20 min)
• Next steps and discussion (20 min)

Speakers/collaborating partners

Dr. Nunzia Linzalone (Institute of Clinical Physiology, Italy)

Dr.Martin Paparella (Medical University Innsbruck, Austria)

Dr. Alexandra Schaffert (Medical University Innsbruck, Austria)

Mr. Edoardo Luca Vigano’ (Mario Negri Institute for Pharmacological Research, Italy)

Dr.Birgit Mertens (Sciensano)

Dr. Sivakumar Murugadoss (Sciensano)

Who should attend this:  regulatory and scientific experts in the fields of risk assessment, environmental health, epidemiology, toxicology, cardiology, new approach methods, next generation risk assessment

registration link: https://www.eventbrite.co.uk/e/evaluation-of-chemical-induced-cardiotoxicity-challenges-and-progress-tickets-531905061357